Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | P2RY6 | Q15077 | 4/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.32 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13615885 | 0.85 | P2RY6 (0.49) | ABL1RIN1P2RY6P2RY14NT5E | |
| SCHEMBL2972166 | 0.79 | P2RY6 (0.44) | ABL1RIN1P2RY6P2RY14NT5E | |
| SCHEMBL2972162 | 0.79 | P2RY6 (0.44) | ABL1RIN1P2RY6P2RY14NT5E | |
| SCHEMBL13615540 | 0.78 | PRMT6 (0.46) | P2RY6CYP3A4ADORA3ADORA2AADORA1 | |
| SCHEMBL19407903 | 0.77 | POLB (0.42) | ABL1RIN1P2RY6P2RY14NT5E | |
| SCHEMBL1096454 | 0.76 | ABL1 (0.42) | ABL1RIN1P2RY6P2RY14NT5E | |
| SCHEMBL19814666 | 0.76 | ABL1 (0.42) | ABL1RIN1P2RY6P2RY14NT5E | |
| SCHEMBL14929222 | 0.76 | ABL1 (0.42) | ABL1RIN1P2RY6P2RY14NT5E | |
| SCHEMBL17614013 | 0.76 | ABL1 (0.39) | ABL1RIN1P2RY6P2RY14NT5E | |
| SCHEMBL26499782 | 0.76 | ABL1 (0.42) | ABL1RIN1P2RY6P2RY14NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143369-A2 | METHOD OF PREPARING NUCLEOSIDES AND ANALOGS THEREOF WITHOUT USING CHROMATOGRAPHY | ISIS PHARMACEUTICALS, INC. (US) | 2009-11-26 | — | — | WO | disclosed |