Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6846096 | 0.91 | BRD4 (0.35) | BRD4 | |
| SCHEMBL8277866 | 0.89 | BRD4 (0.37) | BRD4 | |
| SCHEMBL7950678 | 0.83 | BRD4 (0.33) | BRD4 | |
| SCHEMBL8269502 | 0.79 | BRD4 (0.35) | BRD4 | |
| SCHEMBL14845339 | 0.79 | BRD4 (0.38) | BRD4 | |
| SCHEMBL15044209 | 0.74 | BRD4 (0.32) | BRD4 | |
| SCHEMBL8269512 | 0.71 | BRD4 (0.38) | BRD4 | |
| SCHEMBL16140055 | 0.69 | BRD4 (0.57) | BRD4 | |
| SCHEMBL12332636 | 0.68 | HCN4 (0.55) | BRD4 | |
| SCHEMBL15858417 | 0.68 | BRD4 (0.63) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1614687-B1 | Process for the preparation of 1,3,4,5-tetrahydro-2H-3-benzazepin-2-one derivatives and their application in the synthesis of ivabradine and its pharmaceutically acceptable salts | SERVIER LAB (FR) | 2009-11-11 | — | — | EP | disclosed |