SCHEMBL15044209

SCHEMBL15044209

O=C1Cc2cc(CO)c(CO)cc2C=CN1CCCC1OCCO1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15043263 0.93 BRD4 (0.33) BRD4
SCHEMBL15047162 0.82 BRD4 (0.55) BRD4
SCHEMBL14845339 0.82 BRD4 (0.38) BRD4
SCHEMBL6846096 0.82 BRD4 (0.35) BRD4
SCHEMBL15044211 0.74 HCN4 (0.39)
SCHEMBL7950678 0.74 BRD4 (0.33) BRD4
SCHEMBL16140055 0.73 BRD4 (0.57) BRD4
SCHEMBL15043264 0.68 HCN4 (0.35)
SCHEMBL6848710 0.68 HCN4 (0.57) BRD4
SCHEMBL16140066 0.67 MEN1 (0.42) BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8513410-B2 Process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid LES LABORATOIRES SERVIER (FR) 2013-08-20 US disclosed
US-20130158256-A1 PROCESS FOR THE SYNTHESIS OF IVABRADINE AND ADDITION SALTS THEREOF WITH A PHARMACEUTICALLY ACCEPTABLE ACID LES LABORATOIRES SERVIER (FR) 2013-06-20 US disclosed