Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 9/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CBX7 | O95931 | 1/20 | 0.34 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.34 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.34 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13616106 | 0.95 | MEN1 (0.38) | NPC1MEN1KMT2AACKR3POLB | |
| SCHEMBL13616095 | 0.91 | NPC1 (0.41) | NPC1MEN1KMT2APOLBRAB9A | |
| SCHEMBL13616080 | 0.90 | NPC1 (0.38) | NPC1MEN1KMT2AACKR3POLB | |
| SCHEMBL13616084 | 0.90 | NPC1 (0.42) | NPC1MEN1KMT2APOLBRAB9A | |
| SCHEMBL13616098 | 0.89 | MEN1 (0.38) | NPC1MEN1KMT2APOLBRAB9A | |
| SCHEMBL13747010 | 0.89 | NPC1 (0.38) | NPC1MEN1KMT2AACKR3POLB | |
| SCHEMBL13616105 | 0.89 | NPC1 (0.38) | NPC1MEN1KMT2APOLBRAB9A | |
| SCHEMBL13616089 | 0.85 | NPC1 (0.41) | NPC1MEN1KMT2APOLBRAB9A | |
| SCHEMBL13616079 | 0.85 | MEN1 (0.39) | NPC1MEN1KMT2AACKR3POLB | |
| SCHEMBL13616096 | 0.85 | NPC1 (0.40) | NPC1MEN1KMT2APOLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275538-A1 | ARYLMETHYLIDENE HETEROCYCLES AS NOVEL ANALGESICS | UNIVERSITE LAVAL (CA) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275538-A1 | ARYLMETHYLIDENE HETEROCYCLES AS NOVEL ANALGESICS | OPRL1, OPRK1, AHR | NPC1 2712/4885MEN1 4697/4885KMT2A 1752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.