Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 20/20 | 0.70 |
| ▸ | HSP90AA1 | P07900 | 19/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12613185 | 0.88 | HSP90AB1 (0.61) | HSP90AB1HSP90AA1 | |
| SCHEMBL13539628 | 0.83 | HSP90AB1 (0.55) | HSP90AB1HSP90AA1 | |
| SCHEMBL1060173 | 0.82 | HSP90AA1 (1.00) | HSP90AB1HSP90AA1 | |
| SCHEMBL12612951 | 0.79 | HSP90AA1 (0.60) | HSP90AB1HSP90AA1 | |
| SCHEMBL12613167 | 0.77 | HSP90AA1 (0.67) | HSP90AB1HSP90AA1 | |
| SCHEMBL13539741 | 0.76 | HSP90AB1 (0.47) | HSP90AB1HSP90AA1 | |
| SCHEMBL12613280 | 0.76 | HSP90AA1 (0.78) | HSP90AB1HSP90AA1 | |
| SCHEMBL3089009 | 0.75 | HSP90AA1 (0.84) | HSP90AB1HSP90AA1 | |
| SCHEMBL12613292 | 0.74 | HSP90AA1 (0.75) | HSP90AB1HSP90AA1 | |
| SCHEMBL13160151 | 0.74 | HSP90AB1 (0.54) | HSP90AB1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009139834-A1 | BIOACTIVE COMPOUNDS FOR TREATMENT OF CANCER AND NEURODEGENERATIVE DISEASES | PONIARD PHARMACEUTICALS, INC. (US) | 2009-11-19 | — | — | WO | disclosed |