Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.34 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13616467 | 0.85 | SMN1; SMN2 (0.47) | CA12CA9NPC1RAB9AL3MBTL1 | |
| SCHEMBL13616483 | 0.81 | HDAC3 (0.41) | IGF1RL3MBTL1ALDH1A1MAPTKDM4E | |
| SCHEMBL13616481 | 0.81 | CYP2A6 (0.52) | CA12CA9IGF1RALDH1A1MAPT | |
| SCHEMBL4309343 | 0.81 | CA12 (0.49) | CA12CA9CXCR1IGF1RNPC1 | |
| SCHEMBL13616475 | 0.79 | HDAC3 (0.43) | NPC1RAB9AGAAL3MBTL1ALDH1A1 | |
| SCHEMBL13616471 | 0.78 | DRD2 (0.46) | CXCR1IGF1RNPC1RAB9AALDH1A1 | |
| SCHEMBL13616468 | 0.78 | NOTUM (0.48) | CXCR1NPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL13616469 | 0.78 | NOTUM (0.51) | CXCR1IGF1RNPC1RAB9AL3MBTL1 | |
| SCHEMBL13616476 | 0.76 | DRD2 (0.41) | GAAL3MBTL1ALDH1A1MAPTKDM4E | |
| SCHEMBL13616473 | 0.76 | HDAC3 (0.39) | IGF1RALDH1A1MAPTHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275594-A1 | 3-HYDRAZONE PIPERAZINYL RIFAMYCIN DERIVATIVES USEFUL AS ANTIMICROBIAL AGENTS | JANSSEN PHARMACEUTICA NV (BE) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275594-A1 | 3-HYDRAZONE PIPERAZINYL RIFAMYCIN DERIVATIVES USEFUL AS ANTIMICROBIAL AGENTS | RIF1, ABCC1, HDAC6 | CA12 4834/4885CA9 4475/4885CXCR1 3625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.