SCHEMBL13616672

SCHEMBL13616672

Cn1c(C(O)C=O)nc2ccccc2c1=O

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.53
NPC1 O15118 4/20 0.50
RAB9A P51151 4/20 0.50
ALDH1A1 P00352 2/20 0.49
MAPT P10636 1/20 0.49
HDAC6 Q9UBN7 2/20 0.48
AURKB Q96GD4 1/20 0.47
USP2 O75604 1/20 0.47
CACNA2D1 P54289 1/20 0.46
RXFP1 Q9HBX9 1/20 0.45
LMNA P02545 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
BACE1 P56817 1/20 0.44
PKM P14618 1/20 0.43
TDP1 Q9NUW8 2/20 0.43
POLB P06746 1/20 0.43
TSHR P16473 1/20 0.42
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6979700 0.80 KDM4E (0.60) KDM4ENPC1RAB9AALDH1A1MAPT
SCHEMBL3816839 0.77 KDM4E (0.57) KDM4ENPC1RAB9AALDH1A1MAPT
SCHEMBL13725597 0.77 KDM4E (0.61) KDM4ENPC1RAB9AALDH1A1MAPT
SCHEMBL453901 0.75 KDM4E (0.54) KDM4ENPC1RAB9AALDH1A1MAPT
SCHEMBL12068787 0.72 NPC1 (0.68) KDM4ENPC1RAB9AALDH1A1MAPT
SCHEMBL1101889 0.71 KDM4E (0.66) KDM4ENPC1RAB9AALDH1A1MAPT
SCHEMBL13343631 0.70 KDM4E (0.60) KDM4ENPC1RAB9AALDH1A1MAPT
SCHEMBL24724573 0.70 ALDH1A1 (0.47) KDM4EALDH1A1MAPTLMNATDP1
SCHEMBL24724635 0.70 ALDH1A1 (0.47) KDM4EALDH1A1MAPTLMNATDP1
SCHEMBL1668680 0.70 CACNA2D1 (0.57) KDM4ENPC1RAB9AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1197799-B1 Silver halide photographic light-sensitive material comprising a yellow dye-forming coupler, and method for producing a yellow azomethine dye FUJIFILM CORP (JP) 2009-11-11 EP disclosed