Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.59 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.56 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.56 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL541 | 0.90 | AGTR1 (0.69) | AGTR1AGTR2ABCC4ABCB11PDE3B | |
| SCHEMBL397 | 0.89 | PPARG (0.58) | PPARGAGTR1AGTR2ABCC4ABCB11 | |
| SCHEMBL214 | 0.86 | PPARG (0.56) | PPARGAGTR1AGTR2ABCC4ABCB11 | |
| SCHEMBL13277425 | 0.85 | PPARG (0.55) | PPARGAGTR1AGTR2ABCC4ABCB11 | |
| SCHEMBL9843803 | 0.85 | PPARG (0.58) | PPARGAGTR1 | |
| SCHEMBL3460736 | 0.84 | AGTR1 (0.62) | PPARGAGTR1AGTR2ABCC4ABCB11 | |
| SCHEMBL12716746 | 0.84 | PPARG (0.60) | PPARGAGTR1AGTR2ABCC4ABCB11 | |
| SCHEMBL17949543 | 0.84 | PPARG (0.57) | PPARGAGTR1AGTR2 | |
| SCHEMBL10589345 | 0.84 | PPARG (0.59) | PPARGAGTR1AGTR2ABCC4ABCB11 | |
| SCHEMBL12716740 | 0.83 | PPARG (0.61) | PPARGAGTR1AGTR2ABCC4ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2116548-A1 | PROCESS FOR THE PREPARATION OF TETRAZOLE DERIVATIVES FROM ORGANO BORON AND ORGANO ALUMINIUM AZIDES | Novartis AG (CH) | 2009-11-11 | — | — | EP | disclosed |