Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25850162 | 0.76 | — | — | |
| SCHEMBL9718258 | 0.73 | — | — | |
| SCHEMBL20610005 | 0.69 | TSHR (0.59) | TSHR | |
| SCHEMBL20886547 | 0.68 | OPRM1 (0.37) | — | |
| SCHEMBL24224784 | 0.67 | TSHR (0.50) | TSHR | |
| SCHEMBL21925388 | 0.67 | TSHR (0.50) | TSHR | |
| SCHEMBL56451 | 0.66 | — | — | |
| SCHEMBL19043477 | 0.66 | TSHR (0.43) | TSHR | |
| SCHEMBL2783587 | 0.65 | TSHR (0.48) | TSHR | |
| SCHEMBL21872409 | 0.64 | TSHR (0.42) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2119716-A1 | AZA-BRIDGED-RING COMPOUND | Astellas Pharma Inc. (JP) | 2009-11-18 | — | — | EP | disclosed |