Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 20/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3841052 | 0.90 | CRHR1 (0.71) | CRHR1 | |
| SCHEMBL3843157 | 0.90 | CRHR1 (0.71) | CRHR1 | |
| SCHEMBL3846142 | 0.88 | CRHR1 (0.64) | CRHR1 | |
| SCHEMBL3839329 | 0.87 | CRHR1 (0.62) | CRHR1 | |
| SCHEMBL3839327 | 0.87 | CRHR1 (0.62) | CRHR1 | |
| SCHEMBL13616934 | 0.86 | CRHR1 (0.56) | CRHR1 | |
| SCHEMBL3845337 | 0.85 | CRHR1 (0.64) | CRHR1 | |
| SCHEMBL3840892 | 0.84 | CRHR1 (0.62) | CRHR1 | |
| SCHEMBL3838991 | 0.83 | CRHR1 (0.58) | CRHR1 | |
| SCHEMBL3840649 | 0.83 | CRHR1 (0.61) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446387-B1 | SUBSTITUTED ARYL 1,4-PYRAZINE DERIVATIVES | PHARMACIA & UPJOHN CO LLC (US) | 2009-11-04 | — | — | EP | disclosed |