Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 20/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3840945 | 0.93 | CRHR1 (0.49) | CRHR1 | |
| SCHEMBL3840943 | 0.93 | CRHR1 (0.49) | CRHR1 | |
| SCHEMBL3838635 | 0.91 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL3838636 | 0.91 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL13616683 | 0.91 | CRHR1 (0.48) | CRHR1 | |
| SCHEMBL3843437 | 0.85 | CRHR1 (0.50) | CRHR1 | |
| SCHEMBL3843441 | 0.85 | CRHR1 (0.50) | CRHR1 | |
| SCHEMBL3843442 | 0.85 | CRHR1 (0.50) | CRHR1 | |
| SCHEMBL3845886 | 0.84 | CRHR1 (0.51) | CRHR1 | |
| SCHEMBL3845881 | 0.84 | CRHR1 (0.51) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446387-B1 | SUBSTITUTED ARYL 1,4-PYRAZINE DERIVATIVES | PHARMACIA & UPJOHN CO LLC (US) | 2009-11-04 | — | — | EP | disclosed |