Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PPM1B | O75688 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10289783 | 0.98 | TP53 (0.46) | ALDH1A1TP53CYP3A4MEN1KMT2A | |
| SCHEMBL2295020 | 0.98 | TP53 (0.46) | ALDH1A1TP53CYP3A4MEN1KMT2A | |
| SCHEMBL763361 | 0.98 | TP53 (0.46) | ALDH1A1TP53CYP3A4MEN1KMT2A | |
| SCHEMBL16508896 | 0.94 | TP53 (0.42) | ALDH1A1TP53CYP3A4CA12CA1 | |
| SCHEMBL18635630 | 0.86 | CA1 (0.42) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL1169984 | 0.86 | TP53 (0.52) | ALDH1A1TP53CYP3A4MEN1KMT2A | |
| SCHEMBL1170182 | 0.86 | TP53 (0.52) | ALDH1A1TP53CYP3A4MEN1KMT2A | |
| SCHEMBL1169988 | 0.86 | TP53 (0.52) | ALDH1A1TP53CYP3A4MEN1KMT2A | |
| SCHEMBL4617750 | 0.85 | ALDH1A1 (0.41) | ALDH1A1TP53CYP3A4MEN1KMT2A | |
| SCHEMBL11296878 | 0.84 | CYP3A4 (0.41) | ALDH1A1TP53CYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2119716-A1 | AZA-BRIDGED-RING COMPOUND | Astellas Pharma Inc. (JP) | 2009-11-18 | — | — | EP | disclosed |