Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | STK17B | O94768 | 10/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3040167 | 0.82 | STK17B (0.65) | MAPTRAB9ASTK17BKDM4EELANE | |
| SCHEMBL3040165 | 0.82 | STK17B (0.65) | MAPTRAB9ASTK17BKDM4EELANE | |
| SCHEMBL12886570 | 0.82 | STK17B (0.56) | MAPTRAB9ASMN1; SMN2STK17BACHE | |
| SCHEMBL13617110 | 0.82 | MAOB (0.67) | MAPTRAB9ASTK17BKDM4EACHE | |
| SCHEMBL19462864 | 0.81 | ELANE (0.74) | MAPTRAB9ASMN1; SMN2STK17BKDM4E | |
| SCHEMBL3045002 | 0.77 | STK17B (0.59) | MAPTSTK17BKDM4EACHEMEN1 | |
| SCHEMBL3045006 | 0.77 | STK17B (0.59) | MAPTSTK17BKDM4EACHEMEN1 | |
| SCHEMBL5707799 | 0.76 | MAOB (0.77) | MAPTRAB9ASMN1; SMN2STK17BKDM4E | |
| SCHEMBL3042357 | 0.73 | STK17B (0.55) | MAPTSTK17BKDM4EACHEMEN1 | |
| SCHEMBL3042360 | 0.73 | STK17B (0.55) | MAPTSTK17BKDM4EACHEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2113258-A1 | AURONE DERIVATIVE-CONTAINING COMPOSITION FOR DIAGNOSIS | Nagasaki University (JP) | 2009-11-04 | — | — | EP | disclosed |