Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.67 |
| ▸ | ACHE | P22303 | 1/20 | 0.67 |
| ▸ | STK17B | O94768 | 3/20 | 0.62 |
| ▸ | AURKA | O14965 | 2/20 | 0.62 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.62 |
| ▸ | GSK3B | P49841 | 2/20 | 0.62 |
| ▸ | BLK | P51451 | 2/20 | 0.62 |
| ▸ | BTK | Q06187 | 2/20 | 0.62 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.62 |
| ▸ | DAPK2 | Q9UIK4 | 2/20 | 0.62 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.62 |
| ▸ | TEK | Q02763 | 1/20 | 0.62 |
| ▸ | ITK | Q08881 | 1/20 | 0.62 |
| ▸ | KIT | P10721 | 1/20 | 0.62 |
| ▸ | IKBKB | O14920 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13617106 | 0.84 | MAOB (0.67) | MAOBACHESTK17BAURKADAPK3 | |
| SCHEMBL3040167 | 0.82 | STK17B (0.65) | MAOBSTK17BAURKADAPK3GSK3B | |
| SCHEMBL3040165 | 0.82 | STK17B (0.65) | MAOBSTK17BAURKADAPK3GSK3B | |
| SCHEMBL3045006 | 0.82 | STK17B (0.59) | MAOBACHESTK17BAURKADAPK3 | |
| SCHEMBL3045002 | 0.82 | STK17B (0.59) | MAOBACHESTK17BAURKADAPK3 | |
| SCHEMBL12886570 | 0.82 | STK17B (0.56) | MAOBACHESTK17BAURKADAPK3 | |
| SCHEMBL13616978 | 0.82 | MAPT (0.65) | ACHESTK17BAURKADAPK3GSK3B | |
| SCHEMBL8125901 | 0.81 | ACHE (0.71) | MAOBACHESTK17BAURKADAPK3 | |
| SCHEMBL10889077 | 0.81 | RAB9A (0.64) | MAOBACHESTK17BAURKADAPK3 | |
| SCHEMBL10733193 | 0.81 | RAB9A (0.64) | MAOBACHESTK17BAURKADAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2113258-A1 | AURONE DERIVATIVE-CONTAINING COMPOSITION FOR DIAGNOSIS | Nagasaki University (JP) | 2009-11-04 | — | — | EP | disclosed |