Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 11/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | RORA | P35398 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | RORB | Q92753 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL215195 | 0.83 | CNR2 (0.48) | CNR2CNR1ALDH1A1MAPTTDP1 | |
| SCHEMBL215196 | 0.81 | CNR2 (0.46) | CNR2CNR1KDM4EALDH1A1MAPT | |
| SCHEMBL2760206 | 0.78 | L3MBTL1 (0.48) | CNR2CNR1KDM4EUSP2ALDH1A1 | |
| SCHEMBL2736607 | 0.77 | CYP19A1 (0.35) | KDM4EUSP2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL216494 | 0.72 | CNR2 (0.52) | CNR2CNR1KDM4EALDH1A1MAPT | |
| SCHEMBL217634 | 0.72 | CNR2 (0.49) | CNR2CNR1ALDH1A1MAPTTDP1 | |
| SCHEMBL216146 | 0.72 | CNR2 (0.49) | CNR2CNR1KDM4EUSP2ALDH1A1 | |
| SCHEMBL216181 | 0.71 | CNR2 (0.54) | CNR2CNR1KDM4ETDP1L3MBTL1 | |
| SCHEMBL2760076 | 0.69 | CNR2 (0.52) | CNR2CNR1KDM4EALDH1A1MAPT | |
| SCHEMBL215944 | 0.69 | CNR2 (0.63) | CNR2CNR1KDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477186-B1 | ANTIPRURITICS | SHIONOGI & CO (JP) | 2009-11-11 | — | — | EP | disclosed |