Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7816159 | 1.00 | ADRB3 (0.47) | ADRB3ADRA2BADRA2CCYP3A4GAA | |
| SCHEMBL2238925 | 1.00 | ADRB3 (0.47) | ADRB3ADRA2BADRA2CCYP3A4GAA | |
| SCHEMBL2238934 | 1.00 | ADRB3 (0.47) | ADRB3ADRA2BADRA2CCYP3A4GAA | |
| SCHEMBL2238929 | 1.00 | ADRB3 (0.47) | ADRB3ADRA2BADRA2CCYP3A4GAA | |
| SCHEMBL12349815 | 0.99 | ADRB3 (0.47) | ADRB3ADRA2BADRA2CCYP3A4GAA | |
| SCHEMBL2239472 | 0.91 | ADRB3 (0.42) | ADRB3ADRA2BADRA2CCYP3A4F2 | |
| SCHEMBL2239474 | 0.91 | ADRB3 (0.42) | ADRB3ADRA2BADRA2CCYP3A4F2 | |
| SCHEMBL2239478 | 0.91 | ADRB3 (0.42) | ADRB3ADRA2BADRA2CCYP3A4F2 | |
| SCHEMBL13617075 | 0.91 | ADRB3 (0.42) | ADRB3ADRA2BADRA2CCYP3A4F2 | |
| SCHEMBL7812408 | 0.91 | ADRB3 (0.42) | ADRB3ADRA2BADRA2CCYP3A4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090285773-A1 | Hepatitis C Virus Inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2009-11-19 | — | — | US | disclosed |
| US-20090285773-A1 | Hepatitis C Virus Inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090285773-A1 | Hepatitis C Virus Inhibitors | HAVCR2, HCCS, PYGL | ADRB3 3508/4885ADRA2B 3612/4885ADRA2C 3036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.