Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 14/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.38 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14206630 | 0.88 | CRHR1 (0.49) | CRHR1HSD11B1F2RL3TNKS | |
| SCHEMBL3367536 | 0.85 | CRHR1 (0.49) | CRHR1HSD11B1F2RL3 | |
| SCHEMBL3364750 | 0.84 | CRHR1 (0.48) | CRHR1HSD11B1F2RL3TNKS | |
| SCHEMBL3367449 | 0.82 | CRHR1 (0.46) | CRHR1HSD11B1F2RL3TNKS | |
| SCHEMBL3364408 | 0.82 | CRHR1 (0.46) | CRHR1F2RL3 | |
| SCHEMBL3367441 | 0.82 | CRHR1 (0.47) | CRHR1 | |
| SCHEMBL3399007 | 0.82 | CRHR1 (0.53) | CRHR1HSD11B1F2RL3TNKS | |
| SCHEMBL3364854 | 0.81 | CRHR1 (0.56) | CRHR1HSD11B1F2RL3TNKS | |
| SCHEMBL3846236 | 0.81 | CRHR1 (0.45) | CRHR1 | |
| SCHEMBL3364275 | 0.80 | CRHR1 (0.58) | CRHR1HSD11B1F2RL3TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007753-B1 | HETEROCYCLIC GABA ALPHA SUBTYPE SELECTIVE RECEPTOR MODULATORS | HOFFMANN LA ROCHE (CH) | 2009-11-11 | — | — | EP | disclosed |