Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 16/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 15/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | DRD1 | P21728 | 2/20 | 0.52 |
| ▸ | DRD4 | P21917 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13617478 | 0.87 | ADRB2 (0.64) | ADRB2ADRB1ADRB3CHRM2 | |
| SCHEMBL13617623 | 0.83 | ADRB2 (0.78) | ADRB2ADRB1ADRB3DRD2DRD1 | |
| SCHEMBL13589488 | 0.81 | ADRB2 (0.80) | ADRB2ADRB1ADRB3DRD2DRD1 | |
| SCHEMBL13711797 | 0.80 | ADRB2 (0.62) | ADRB2ADRB1ADRB3DRD2DRD1 | |
| SCHEMBL13617404 | 0.80 | ADRB2 (0.61) | ADRB2ADRB1ADRB3DRD2DRD1 | |
| SCHEMBL13711791 | 0.79 | ADRB2 (0.69) | ADRB2ADRB1ADRB3DRD2DRD1 | |
| SCHEMBL13617642 | 0.79 | ADRB2 (0.52) | ADRB2ADRB1ADRB3 | |
| SCHEMBL13617485 | 0.78 | ADRB2 (0.59) | ADRB2ADRB1ADRB3DRD2DRD1 | |
| SCHEMBL13617660 | 0.78 | ADRB2 (0.54) | ADRB2ADRB1ADRB3DRD2DRD1 | |
| SCHEMBL13708434 | 0.77 | ADRB2 (0.40) | ADRB2ADRB1ADRB3DRD2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1641465-B1 | COMBINATIONS OF AN ARYL ANILINE BETA-2 ADRENERGIC RECEPTOR AGONIST AND A CORTICOSTEROID | THERAVANCE INC (US) | 2009-11-04 | — | — | EP | disclosed |
| EP-1446379-B1 | ARYL ANILINE BETA-2 ADRENERGIC RECEPTOR AGONISTS | THERAVANCE INC (US) | 2009-04-29 | — | — | EP | disclosed |