Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 13/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3389201 | 0.80 | HPGD (0.68) | HPGDKDM4EALDH1A1TSHRHSD11B1 | |
| SCHEMBL3455576 | 0.78 | HPGD (0.66) | HPGDKDM4EALDH1A1TSHRHSD11B1 | |
| SCHEMBL29632673 | 0.77 | HPGD (0.56) | HPGDKDM4EALDH1A1TSHRHSD11B1 | |
| SCHEMBL1495677 | 0.74 | HPGD (0.60) | HPGDKDM4EALDH1A1TSHRHSD11B1 | |
| SCHEMBL971083 | 0.72 | HPGD (1.00) | HPGDALDH1A1TSHRMAPK1 | |
| SCHEMBL12569437 | 0.72 | HPGD (0.96) | HPGDKDM4EALDH1A1TSHRHSD11B1 | |
| SCHEMBL2014694 | 0.72 | KDM4E (1.00) | HPGDKDM4EALDH1A1HSD11B1SERPINE1 | |
| SCHEMBL10721733 | 0.72 | HPGD (0.95) | HPGDKDM4EALDH1A1TSHRMAPK1 | |
| SCHEMBL18734483 | 0.72 | HPGD (0.57) | HPGDKDM4EALDH1A1TSHRHSD11B1 | |
| SCHEMBL24185725 | 0.71 | HPGD (0.96) | HPGDALDH1A1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067638-B2 | Amide derivative and insecticide containing the same | MITSUI CHEMICALS, INC. (JP) | 2011-11-29 | — | — | US | disclosed |
| US-20090233962-A1 | Amide derivative and insecticide containing the same | MITSUI CHEMICALS, INC. (JP) | 2009-09-17 | — | — | US | disclosed |
| EP-1911751-A1 | AMIDE DERIVATIVE AND PESTICIDE CONTAINING SUCH COMPOUND | Mitsui Chemicals, Inc. (JP) | 2008-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233962-A1 | Amide derivative and insecticide containing the same | CYP1A1, CYP4B1, CYP2E1 | HPGD 2086/4885KDM4E 496/4885ALDH1A1 427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.