Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.50 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | THRA | P10827 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13980327 | 0.93 | ESR1 (0.44) | ESR1NUDT1BACE1HSP90AA1CACNA1B | |
| SCHEMBL20717732 | 0.93 | ESR1 (0.51) | ESR1NUDT1BACE1HSP90AA1CACNA1B | |
| SCHEMBL29368513 | 0.92 | NUDT1 (0.50) | ESR1NUDT1BACE1HSP90AA1CACNA1B | |
| SCHEMBL68186 | 0.92 | NUDT1 (0.50) | ESR1NUDT1BACE1HSP90AA1CACNA1B | |
| SCHEMBL29623103 | 0.91 | NUDT1 (0.49) | ESR1NUDT1BACE1HSP90AA1CACNA1B | |
| SCHEMBL13609954 | 0.91 | NUDT1 (0.49) | ESR1NUDT1BACE1HSP90AA1CACNA1B | |
| SCHEMBL20717758 | 0.87 | ESR1 (0.47) | ESR1NUDT1BACE1HSP90AA1CACNA1B | |
| SCHEMBL2340495 | 0.87 | ESR1 (0.49) | ESR1NUDT1BACE1HSP90AA1CACNA1B | |
| SCHEMBL29458615 | 0.87 | ESR1 (0.49) | ESR1NUDT1BACE1HSP90AA1CACNA1B | |
| SCHEMBL17354422 | 0.87 | NUDT1 (0.46) | ESR1NUDT1BACE1HSP90AA1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133456-A1 | SPIN-ON GRADED K SILICON ANTIREFLECTIVE COATING | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2009-11-05 | — | — | WO | disclosed |