Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | STS | P08842 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL184777 | 0.88 | CYP2D6 (0.60) | GPR119MMP13KMT2ASTSMEN1 | |
| SCHEMBL28719877 | 0.84 | CYP2D6 (0.55) | GPR119MMP13KMT2ASTSMEN1 | |
| SCHEMBL5447212 | 0.84 | CYP2D6 (0.55) | GPR119MMP13KMT2ASTSMEN1 | |
| SCHEMBL19001727 | 0.84 | CYP2D6 (0.55) | GPR119MMP13KMT2ASTSMEN1 | |
| SCHEMBL222877 | 0.83 | CYP2D6 (0.54) | GPR119MMP13KMT2ASTSMEN1 | |
| SCHEMBL221064 | 0.83 | CYP2D6 (0.54) | GPR119MMP13KMT2ASTSMEN1 | |
| SCHEMBL221063 | 0.83 | CYP2D6 (0.54) | GPR119MMP13KMT2ASTSMEN1 | |
| SCHEMBL15600231 | 0.83 | GPR119 (0.53) | GPR119MMP13KMT2ASTSMEN1 | |
| SCHEMBL25213322 | 0.82 | GPR119 (0.58) | GPR119MMP13KMT2ASTSTP53 | |
| SCHEMBL30750650 | 0.81 | GPR119 (0.51) | GPR119MMP13KMT2ASTSMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943240-B1 | CHEMICAL PROCESS | ASTRAZENECA AB (SE) | 2009-11-11 | — | — | EP | disclosed |