⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25419169 | 0.76 | — | — | |
| SCHEMBL4428965 | 0.75 | — | — | |
| SCHEMBL15459195 | 0.74 | LMNA (0.31) | — | |
| SCHEMBL20409287 | 0.71 | CYP2C9 (0.33) | — | |
| SCHEMBL11819919 | 0.70 | — | — | |
| SCHEMBL10456597 | 0.70 | — | — | |
| SCHEMBL12394118 | 0.69 | — | — | |
| SCHEMBL11584532 | 0.68 | — | — | |
| SCHEMBL10935283 | 0.68 | LMNA (0.31) | — | |
| SCHEMBL3645316 | 0.68 | LMNA (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833816-B1 | SUBSTITUTED PIPERIDINES AS RENIN INHIBITORS | NOVARTIS AG (CH) | 2009-11-11 | — | — | EP | disclosed |