Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.49 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30317585 | 0.84 | FDPS (0.63) | FDPSALDH1A1MAPTNPSR1HTT | |
| SCHEMBL2945520 | 0.84 | FDPS (0.63) | FDPSALDH1A1MAPTNPSR1HTT | |
| SCHEMBL30317632 | 0.84 | FDPS (0.63) | FDPSALDH1A1MAPTNPSR1HTT | |
| SCHEMBL2948173 | 0.84 | FDPS (0.63) | FDPSALDH1A1MAPTNPSR1HTT | |
| SCHEMBL5053914 | 0.84 | FDPS (0.63) | FDPSALDH1A1MAPTNPSR1HTT | |
| SCHEMBL10497454 | 0.84 | FDPS (0.63) | FDPSALDH1A1MAPTNPSR1HTT | |
| SCHEMBL10497979 | 0.84 | FDPS (0.63) | FDPSALDH1A1MAPTNPSR1HTT | |
| SCHEMBL8373569 | 0.84 | FDPS (0.63) | FDPSALDH1A1MAPTNPSR1HTT | |
| SCHEMBL10497561 | 0.84 | FDPS (0.63) | FDPSALDH1A1MAPTNPSR1HTT | |
| SCHEMBL30317637 | 0.84 | FDPS (0.63) | FDPSALDH1A1MAPTNPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575964-B1 | N-(BENZYL)AMINOALKYL CARBOXYLATE, PHOSPHINATES, PHOSPHONATES AND TETRAZOLES AS EDG RECEPTOR AGONISTS | MERCK & CO INC (US) | 2009-11-11 | — | — | EP | disclosed |