Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 11/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1134342 | 1.00 | OPRL1 (0.43) | OPRL1OPRM1OPRK1MAPK1 | |
| SCHEMBL1134340 | 1.00 | OPRL1 (0.43) | OPRL1OPRM1OPRK1MAPK1 | |
| SCHEMBL1134343 | 1.00 | OPRL1 (0.43) | OPRL1OPRM1OPRK1MAPK1 | |
| SCHEMBL1134406 | 1.00 | OPRL1 (0.43) | OPRL1OPRM1OPRK1MAPK1 | |
| SCHEMBL1134316 | 0.93 | OPRM1 (0.42) | OPRL1OPRM1OPRK1 | |
| SCHEMBL1134391 | 0.93 | OPRM1 (0.42) | OPRL1OPRM1OPRK1 | |
| SCHEMBL1134488 | 0.93 | OPRM1 (0.42) | OPRL1OPRM1OPRK1 | |
| SCHEMBL1134348 | 0.93 | OPRM1 (0.42) | OPRL1OPRM1OPRK1 | |
| SCHEMBL1134375 | 0.93 | OPRM1 (0.41) | OPRL1OPRM1OPRK1 | |
| SCHEMBL1134350 | 0.93 | OPRM1 (0.41) | OPRL1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275574-A1 | NOVEL COMPOUNDS-300 | ASTRAZENECA AB (SE) | 2009-11-05 | — | — | US | disclosed |
| US-20090275574-A1 | NOVEL COMPOUNDS-300 | ASTRAZENECA AB (SE) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275574-A1 | NOVEL COMPOUNDS-300 | CACNA1A, SCN10A, OPRM1 | OPRL1 4/4885OPRM1 3/4885OPRK1 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.