Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TTK | P33981 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1901638 | 0.80 | KDM4E (0.61) | KDM4ESTAT3HIF1ASMN1; SMN2MAP2K4 | |
| SCHEMBL5565435 | 0.79 | PDE5A (0.56) | KDM4EHIF1ASMN1; SMN2MAP2K4ALDH1A1 | |
| SCHEMBL3232557 | 0.76 | KDM4E (0.62) | KDM4ESTAT3HIF1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3240192 | 0.75 | MAP2K4 (0.56) | KDM4ESTAT3HIF1AMAP2K4ALDH1A1 | |
| SCHEMBL4300704 | 0.74 | SMN1; SMN2 (0.71) | KDM4ESTAT3HIF1ASMN1; SMN2EGFR | |
| SCHEMBL23909017 | 0.71 | SMN1; SMN2 (0.66) | KDM4ESTAT3HIF1ASMN1; SMN2EGFR | |
| SCHEMBL13618347 | 0.71 | PDE5A (0.71) | KDM4EHIF1ASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL17581887 | 0.70 | HSP90AB1 (0.50) | KDM4ESMN1; SMN2ALDH1A1RAB9AGAA | |
| Acetic Acid Methyl Ester SCHEMBL15622680 | 0.69 | KDM4E (0.69) | KDM4ESTAT3HIF1ASMN1; SMN2MAP2K4 | |
| SCHEMBL14497193 | 0.68 | KDM4E (0.49) | KDM4ESMN1; SMN2MAP2K4ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425011-B1 | ENHANCEMENT OF LEARNING AND MEMORY AND TREATMENT OF AMNESIA | CARLSBAD TECHNOLOGY INC (US) | 2009-11-04 | — | — | EP | disclosed |
| EP-1331223-B1 | Method of treating sepsis | YUNG SHIN PHARMACEUTICAL IND (TW) | 2008-02-13 | — | — | EP | disclosed |