Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.72 |
| ▸ | TP53 | P04637 | 3/20 | 0.72 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.72 |
| ▸ | GLA | P06280 | 1/20 | 0.72 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.57 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.56 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.56 |
| ▸ | ITGAV | P06756 | 1/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.56 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.56 |
| ▸ | NT5E | P21589 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13593586 | 0.87 | NR1H4 (0.58) | MEN1KMT2ATP53FFAR1GLA | |
| SCHEMBL10102714 | 0.85 | NR1H4 (0.72) | MEN1KMT2AFFAR1NR1H4NPC1 | |
| SCHEMBL14595003 | 0.85 | ITGB3 (0.59) | MEN1KMT2ATP53FFAR1GLA | |
| SCHEMBL13814818 | 0.85 | NR1H4 (0.58) | MEN1KMT2ATP53FFAR1GLA | |
| SCHEMBL2060736 | 0.85 | NR1H4 (0.58) | MEN1KMT2ATP53FFAR1GLA | |
| SCHEMBL5659023 | 0.84 | NPC1 (0.66) | MEN1KMT2ATP53NR1H4NPC1 | |
| SCHEMBL1468045 | 0.84 | NR1H4 (0.58) | MEN1KMT2ATP53FFAR1GLA | |
| SCHEMBL31661752 | 0.84 | NPC1 (0.66) | MEN1KMT2ATP53NR1H4NPC1 | |
| SCHEMBL12725161 | 0.83 | KMT2A (0.69) | MEN1KMT2ATP53FFAR1GLA | |
| SCHEMBL14088989 | 0.82 | NR1H4 (0.81) | MEN1KMT2AFFAR1NR1H4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9370492-B2 | Solid pharmaceutical dosage forms comprising bisphosphonates and modified amino acid carriers | EMISPHERE TECHNOLOGIES, INC. (US) | 2016-06-21 | — | — | US | disclosed |
| US-20090281064-A1 | SOLID PHARMACEUTICAL DOSAGE FORMS COMPRISING BISPHOSPHONATES AND MODIFIED AMINO ACID CARRIERS | EMISPHERE TECHNOLOGIES, INC. (US) | 2009-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281064-A1 | SOLID PHARMACEUTICAL DOSAGE FORMS COMPRISING BISPHOSPHONATES AND MODIFIED AMINO ACID CARRIERS | SLC1A5, SLC7A5, SLC7A1 | MEN1 379/4885KMT2A 2965/4885TP53 1261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.