Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10146061 | 0.86 | POLB (0.46) | POLBCASP3SENP7SENP6NPC1 | |
| SCHEMBL21397907 | 0.84 | POLB (0.44) | POLBCASP3SENP7SENP6NPC1 | |
| SCHEMBL24752179 | 0.83 | POLB (0.44) | POLBCASP3SENP7SENP6NPC1 | |
| SCHEMBL24753886 | 0.83 | POLB (0.44) | POLBCASP3SENP7SENP6NPC1 | |
| SCHEMBL21397910 | 0.80 | POLB (0.40) | POLBCASP3SENP7SENP6NPC1 | |
| SCHEMBL17115059 | 0.79 | NPC1 (0.47) | POLBCASP3SENP7SENP6NPC1 | |
| SCHEMBL8252792 | 0.79 | POLB (0.46) | POLBCASP3SENP7SENP6NPC1 | |
| SCHEMBL23866629 | 0.78 | POLB (0.40) | POLBCASP3SENP7SENP6NPC1 | |
| SCHEMBL10147515 | 0.76 | POLB (0.39) | POLBCASP3SENP7SENP6NPC1 | |
| SCHEMBL10105655 | 0.76 | HCRTR1 (0.43) | CNR1CNR2HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140089-A2 | SULFONE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-11-19 | — | — | WO | disclosed |