Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13618552 | 0.90 | ALDH1A1 (0.31) | — | |
| SCHEMBL13618715 | 0.80 | CNR2 (0.30) | — | |
| SCHEMBL10147807 | 0.71 | MAPK8 (0.32) | MAPK8 | |
| SCHEMBL10176671 | 0.70 | CNR2 (0.38) | MAPK8 | |
| SCHEMBL352503 | 0.70 | CNR2 (0.38) | MAPK8 | |
| SCHEMBL338018 | 0.62 | TSHR (0.44) | — | |
| SCHEMBL1966898 | 0.61 | GRM1 (0.38) | — | |
| SCHEMBL10086748 | 0.61 | BRD4 (0.43) | — | |
| SCHEMBL337453 | 0.61 | BRD4 (0.43) | — | |
| SCHEMBL337044 | 0.61 | GRM1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140089-A2 | SULFONE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-11-19 | — | — | WO | disclosed |