Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.34 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.34 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13618714 | 0.83 | ALDH1A1 (0.42) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL30838559 | 0.72 | KMT2A (0.47) | ALDH1A1LMNAALOX12MEN1KMT2A | |
| SCHEMBL13618735 | 0.69 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL10147498 | 0.68 | ALDH1A1 (0.42) | ALDH1A1LMNAALOX12MEN1KMT2A | |
| SCHEMBL1417538 | 0.68 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL351405 | 0.67 | CNR2 (0.54) | ALDH1A1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL5740555 | 0.66 | KCNN4 (0.48) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL27625470 | 0.65 | ALDH1A1 (0.50) | ALDH1A1NPC1RAB9AKCNN4IDO1 | |
| SCHEMBL28852614 | 0.65 | KCNN4 (0.47) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL351585 | 0.64 | HPGD (0.41) | ALDH1A1LMNAMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140089-A2 | SULFONE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-11-19 | — | — | WO | disclosed |