⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1067063 | 1.00 | — | — | |
| SCHEMBL21017220 | 0.95 | — | — | |
| SCHEMBL24425442 | 0.90 | — | — | |
| SCHEMBL60925 | 0.90 | — | — | |
| SCHEMBL7026108 | 0.86 | ALDH1A1 (0.36) | — | |
| SCHEMBL868375 | 0.86 | — | — | |
| SCHEMBL708464 | 0.82 | — | — | |
| SCHEMBL24425424 | 0.82 | — | — | |
| SCHEMBL24637544 | 0.78 | — | — | |
| SCHEMBL21017223 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024219479-A1 | NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE | ＥＡファーマ株式会社 | 2024-10-24 | — | — | WO | disclosed |
| US-11718602-B2 | EGFR inhibitors | BLUEPRINT MEDICINES CORPORATION (US) | 2023-08-08 | — | — | US | disclosed |
| EP-2275414-B1 | CYCLOPENTYLACRYLAMIDE DERIVATIVE | KYORIN SEIYAKU KK (JP) | 2015-06-10 | — | — | EP | disclosed |
| EP-2116535-B1 | GLUCOKINASE-ACTIVATING SUBSTANCE | KYORIN SEIYAKU KK (JP) | 2014-06-11 | — | — | EP | disclosed |
| EP-2116533-A1 | GLUCOKINASE ACTIVATOR | Kyorin Pharmaceutical Co., Ltd. (JP) | 2009-11-11 | — | — | EP | disclosed |
| EP-2116535-A1 | GLUCOKINASE-ACTIVATING SUBSTANCE | Kyorin Pharmaceutical Co., Ltd. (JP) | 2009-11-11 | — | — | EP | disclosed |