Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GRN | P28799 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | GALR3 | O60755 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 4/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL351307 | 0.81 | CNR2 (0.49) | KDM4EGRNSORT1CNR2GALR3 | |
| SCHEMBL10147509 | 0.79 | GALR3 (0.43) | KDM4EGRNSORT1CNR2GALR3 | |
| SCHEMBL7985728 | 0.66 | KDM4E (0.67) | KDM4EGRNSORT1CNR2GALR3 | |
| SCHEMBL350954 | 0.65 | KDM4E (0.65) | KDM4EGRNSORT1CNR2GALR3 | |
| SCHEMBL1869664 | 0.65 | LMNA (0.49) | KDM4EGRNSORT1GALR3RAB9A | |
| SCHEMBL766896 | 0.65 | CNR2 (0.57) | CNR2LMNAMAPK14 | |
| SCHEMBL19710054 | 0.64 | SMYD3 (0.66) | KDM4EGRNSORT1GALR3RAB9A | |
| SCHEMBL21490047 | 0.64 | SMYD3 (0.66) | KDM4EGRNSORT1GALR3RAB9A | |
| SCHEMBL14647253 | 0.64 | CNR2 (0.68) | CNR2 | |
| SCHEMBL16358419 | 0.64 | CNR2 (0.61) | CNR2LMNAMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140089-A2 | SULFONE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-11-19 | — | — | WO | disclosed |