Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 9/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.37 |
| ▸ | AR | P10275 | 3/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | IL6 | P05231 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NQO1 | P15559 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1315283 | 0.91 | PGR (0.42) | PGRNR3C1ARNR3C2MAPT | |
| SCHEMBL1780838 | 0.88 | PGR (0.40) | PGRNR3C1ARNR3C2MAPT | |
| SCHEMBL4417572 | 0.87 | PGR (0.42) | PGRNR3C1ARNR3C2MAPT | |
| SCHEMBL4429174 | 0.87 | PGR (0.44) | PGRNR3C1ARNR3C2MAPT | |
| SCHEMBL1315405 | 0.86 | PGR (0.42) | PGRNR3C1ARNR3C2MAPT | |
| SCHEMBL14847583 | 0.85 | PGR (0.48) | PGRNR3C1ARNR3C2MAPT | |
| SCHEMBL1316094 | 0.85 | PGR (0.42) | PGRNR3C1ARNR3C2MAPT | |
| SCHEMBL1314463 | 0.84 | PGR (0.45) | PGRNR3C1ARNR3C2MAPT | |
| SCHEMBL1315958 | 0.83 | PGR (0.43) | PGRNR3C1ARNR3C2MAPT | |
| SCHEMBL448504 | 0.82 | PGR (0.46) | PGRNR3C1ARNR3C2IL6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009139361-A1 | GLUCOCORTICOID RECEPTOR AGONIST COMPOSED OF 2,2,4-TRIMETHYL-6-PHENYL-1,2-DIHYDROQUINOLINE DERIVATIVE HAVING SUBSTITUTED OXY GROUP | 参天製薬株式会社 (JP) | 2009-11-19 | — | — | WO | disclosed |