Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 20/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.57 |
| ▸ | HTR2C | P28335 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1422158 | 1.00 | HTR6 (0.59) | HTR6ADRA2AHTR2C | |
| SCHEMBL1422189 | 0.89 | HTR6 (0.47) | HTR6ADRA2AHTR2C | |
| SCHEMBL14290503 | 0.89 | HTR6 (0.61) | HTR6ADRA2AHTR2C | |
| SCHEMBL1422681 | 0.87 | HTR6 (0.59) | HTR6ADRA2AHTR2C | |
| SCHEMBL750178 | 0.84 | HTR6 (0.61) | HTR6ADRA2AHTR2C | |
| SCHEMBL730733 | 0.84 | HTR6 (0.61) | HTR6ADRA2AHTR2C | |
| SCHEMBL732780 | 0.83 | HTR6 (0.58) | HTR6ADRA2AHTR2C | |
| SCHEMBL749511 | 0.83 | HTR6 (0.58) | HTR6ADRA2AHTR2C | |
| SCHEMBL13947348 | 0.82 | HTR6 (0.64) | HTR6ADRA2AHTR2C | |
| SCHEMBL1421964 | 0.82 | HTR6 (0.62) | HTR6ADRA2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009135925-A1 | SUBSTITUTED N-IMIDAZO[2,1-B]THIAZOLE-5-SULFONAMIDE DERIVATIVES AS 5-HT6 LIGANDS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2009-11-12 | — | — | WO | disclosed |