Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 20/20 | 0.58 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3872223 | 0.89 | SLC6A9 (0.69) | SLC6A9SLC6A5KCNH2 | |
| SCHEMBL3873273 | 0.89 | SLC6A9 (0.58) | SLC6A9SLC6A5KCNH2 | |
| SCHEMBL3880642 | 0.86 | SLC6A9 (0.68) | SLC6A9SLC6A5KCNH2 | |
| SCHEMBL8262337 | 0.83 | SLC6A9 (0.66) | SLC6A9SLC6A5 | |
| SCHEMBL3874401 | 0.83 | SLC6A9 (0.53) | SLC6A9SLC6A5KCNH2 | |
| SCHEMBL1379869 | 0.83 | SLC6A9 (0.56) | SLC6A9SLC6A5KCNH2 | |
| SCHEMBL3878359 | 0.83 | SLC6A9 (0.78) | SLC6A9SLC6A5 | |
| SCHEMBL3872117 | 0.82 | SLC6A9 (0.67) | SLC6A9SLC6A5 | |
| SCHEMBL3873317 | 0.82 | SLC6A9 (0.69) | SLC6A9SLC6A5KCNH2 | |
| SCHEMBL13618781 | 0.81 | SLC6A9 (0.58) | SLC6A9SLC6A5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844045-B1 | PHENYL METHANONE DERIVATIVES AND THEIR USE AS GLYCINE TRANSPORTER 1 INHIBITORS | HOFFMANN LA ROCHE (CH) | 2009-11-04 | — | — | EP | disclosed |