Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24225160 | 0.77 | BCL2L1 (0.31) | — | |
| SCHEMBL29362523 | 0.77 | MAOA (0.33) | SOS1 | |
| SCHEMBL7792883 | 0.77 | MAOA (0.33) | SOS1 | |
| SCHEMBL13451350 | 0.74 | PARP1 (0.33) | SOS1 | |
| SCHEMBL4644733 | 0.73 | MAOA (0.33) | — | |
| SCHEMBL2264771 | 0.70 | AR (0.37) | SOS1HTR2C | |
| SCHEMBL12490226 | 0.70 | MAPT (0.34) | — | |
| SCHEMBL30686151 | 0.70 | MAPT (0.34) | — | |
| SCHEMBL28908910 | 0.70 | MAOA (0.37) | SOS1 | |
| SCHEMBL30047627 | 0.70 | MAOA (0.37) | SOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1848694-B1 | HETEROCYCLIC SUBSTITUTED PHENYL METHANONES AS INHIBITORS OF THE GLYCINE TRANSPORTER 1 | HOFFMANN LA ROCHE (CH) | 2009-11-25 | — | — | EP | disclosed |