Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 20/20 | 0.70 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3876286 | 0.94 | SLC6A9 (0.77) | SLC6A9SLC6A5KCNH2 | |
| SCHEMBL4129873 | 0.89 | SLC6A9 (0.72) | SLC6A9SLC6A5 | |
| SCHEMBL4137807 | 0.83 | SLC6A9 (1.00) | SLC6A9SLC6A5 | |
| SCHEMBL3873799 | 0.83 | SLC6A9 (1.00) | SLC6A9SLC6A5KCNH2 | |
| SCHEMBL3872182 | 0.83 | SLC6A9 (1.00) | SLC6A9SLC6A5KCNH2 | |
| SCHEMBL1462074 | 0.82 | SLC6A9 (0.75) | SLC6A9SLC6A5KCNH2 | |
| SCHEMBL3916682 | 0.82 | SLC6A9 (0.75) | SLC6A9SLC6A5KCNH2 | |
| SCHEMBL4133386 | 0.82 | SLC6A9 (0.78) | SLC6A9SLC6A5 | |
| SCHEMBL3876378 | 0.82 | SLC6A9 (1.00) | SLC6A9SLC6A5 | |
| SCHEMBL3870868 | 0.81 | SLC6A9 (0.84) | SLC6A9SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1848694-B1 | HETEROCYCLIC SUBSTITUTED PHENYL METHANONES AS INHIBITORS OF THE GLYCINE TRANSPORTER 1 | HOFFMANN LA ROCHE (CH) | 2009-11-25 | — | — | EP | disclosed |