⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26518736 | 0.89 | ALDH1A1 (0.36) | — | |
| SCHEMBL26518741 | 0.89 | ALDH1A1 (0.36) | — | |
| SCHEMBL26518750 | 0.89 | ALDH1A1 (0.36) | — | |
| SCHEMBL11567393 | 0.89 | ALDH1A1 (0.36) | — | |
| SCHEMBL26518728 | 0.89 | ALDH1A1 (0.36) | — | |
| SCHEMBL26518724 | 0.89 | ALDH1A1 (0.36) | — | |
| SCHEMBL9056245 | 0.89 | ALDH1A1 (0.36) | — | |
| SCHEMBL26518731 | 0.89 | ALDH1A1 (0.36) | — | |
| SCHEMBL26518755 | 0.89 | ALDH1A1 (0.36) | — | |
| SCHEMBL11570499 | 0.89 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7615543-B2 | Complexes with C-reactive protein (CRP) molecules; rheumatoid arthritis, juvenile chronic (rheumatoid) arthritis, ankylosing spondylitis, psoriatic arthritis, systemic vasculitis, polymyalgia rheumatica, Reiter's disease, Crohn's disease and familial Mediterranean fever | PENTRAXIN THERAPEUTICS LIMITED (GB) | 2009-11-10 | — | — | US | disclosed |
| US-7615543-B2 | Complexes with C-reactive protein (CRP) molecules; rheumatoid arthritis, juvenile chronic (rheumatoid) arthritis, ankylosing spondylitis, psoriatic arthritis, systemic vasculitis, polymyalgia rheumatica, Reiter's disease, Crohn's disease and familial Mediterranean fever | PENTRAXIN THERAPEUTICS LIMITED (GB) | 2009-11-10 | — | — | US | disclosed |