Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 20/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8261794 | 0.94 | SLC6A9 (0.56) | SLC6A9KCNH2SLC6A5 | |
| SCHEMBL3874149 | 0.93 | SLC6A9 (0.64) | SLC6A9KCNH2SLC6A5 | |
| SCHEMBL1382988 | 0.85 | SLC6A9 (0.58) | SLC6A9KCNH2SLC6A5 | |
| SCHEMBL1462234 | 0.84 | SLC6A9 (0.58) | SLC6A9KCNH2SLC6A5 | |
| SCHEMBL3946327 | 0.81 | SLC6A9 (0.79) | SLC6A9KCNH2SLC6A5 | |
| SCHEMBL3872951 | 0.80 | SLC6A9 (0.64) | SLC6A9KCNH2SLC6A5 | |
| SCHEMBL3886404 | 0.77 | SLC6A9 (0.54) | SLC6A9KCNH2SLC6A5 | |
| SCHEMBL1379673 | 0.76 | SLC6A9 (0.66) | SLC6A9KCNH2SLC6A5 | |
| SCHEMBL8261789 | 0.74 | SLC6A9 (0.74) | SLC6A9KCNH2 | |
| SCHEMBL17214308 | 0.73 | SLC6A9 (0.67) | SLC6A9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1848694-B1 | HETEROCYCLIC SUBSTITUTED PHENYL METHANONES AS INHIBITORS OF THE GLYCINE TRANSPORTER 1 | HOFFMANN LA ROCHE (CH) | 2009-11-25 | — | — | EP | disclosed |