Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.43 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.41 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42503 | 1.00 | TRPV1 (0.48) | TRPV1TSHRGAAMAPK10ACHE | |
| SCHEMBL11981735 | 1.00 | TRPV1 (0.48) | TRPV1TSHRGAAMAPK10ACHE | |
| SCHEMBL10104825 | 1.00 | TRPV1 (0.48) | TRPV1TSHRGAAMAPK10ACHE | |
| SCHEMBL42586 | 0.92 | ACHE (0.52) | TRPV1TSHRGAAMAPK10ACHE | |
| SCHEMBL41878 | 0.92 | ACHE (0.52) | TRPV1TSHRGAAMAPK10ACHE | |
| SCHEMBL41877 | 0.92 | ACHE (0.52) | TRPV1TSHRGAAMAPK10ACHE | |
| SCHEMBL42587 | 0.92 | ACHE (0.52) | TRPV1TSHRGAAMAPK10ACHE | |
| SCHEMBL41876 | 0.92 | ACHE (0.52) | TRPV1TSHRGAAMAPK10ACHE | |
| SCHEMBL42742 | 0.89 | TRPV1 (0.44) | TRPV1ACHEBACE1ERCC1ERCC4 | |
| SCHEMBL38412 | 0.89 | ERCC1 (0.44) | TSHRGAAMAPK10ERCC1ERCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136625-A1 | CYCLIC AMINE-1-CARBOXYLIC ACID ESTER DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | 大日本住友製薬株式会社 (JP) | 2009-11-12 | — | — | WO | disclosed |