Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43562 | 0.87 | TRPV1 (0.49) | TRPV1ACHEBACE1CYP3A4CYP2C19 | |
| SCHEMBL42608 | 0.83 | TRPV1 (0.48) | TRPV1ACHEBACE1CYP3A4CYP2C19 | |
| SCHEMBL38771 | 0.80 | TRPV1 (0.53) | TRPV1ACHEBACE1CYP3A4CYP2C19 | |
| SCHEMBL42763 | 0.78 | TRPV1 (0.47) | TRPV1ACHEBACE1CYP3A4CYP2C19 | |
| SCHEMBL43612 | 0.78 | TRPV1 (0.49) | TRPV1ACHEBACE1CYP3A4CYP2C19 | |
| SCHEMBL47188 | 0.78 | TRPV1 (0.49) | TRPV1ACHEBACE1CYP3A4CYP2C19 | |
| SCHEMBL41898 | 0.78 | TRPV1 (0.47) | TRPV1ACHEBACE1CYP3A4CYP2C19 | |
| SCHEMBL42564 | 0.78 | TRPV1 (0.47) | TRPV1ACHEBACE1CYP3A4CYP2C19 | |
| SCHEMBL41897 | 0.78 | TRPV1 (0.47) | TRPV1ACHEBACE1CYP3A4CYP2C19 | |
| SCHEMBL42854 | 0.78 | ACHE (0.49) | TRPV1ACHEBACE1MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136625-A1 | CYCLIC AMINE-1-CARBOXYLIC ACID ESTER DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | 大日本住友製薬株式会社 (JP) | 2009-11-12 | — | — | WO | disclosed |