Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.39 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1831612 | 0.81 | AOC3 (0.44) | AOC3SIGMAR1KDM4ECYP1A2GAA | |
| SCHEMBL31378985 | 0.80 | AOC3 (0.47) | AOC3SIGMAR1KDM4ECYP1A2GAA | |
| SCHEMBL634044 | 0.80 | KDM4E (0.52) | AOC3KDM4ECYP1A2CYP2C9LMNA | |
| SCHEMBL67251 | 0.80 | CYP19A1 (0.41) | MEN1KMT2ALMNANPSR1 | |
| SCHEMBL26109029 | 0.77 | IDO1 (0.32) | MEN1KMT2AGABBR2GABBR1SLC6A3 | |
| SCHEMBL6223969 | 0.77 | IDO1 (0.32) | MEN1KMT2AGABBR2GABBR1SLC6A3 | |
| SCHEMBL5586175 | 0.77 | IDO1 (0.32) | MEN1KMT2AGABBR2GABBR1SLC6A3 | |
| SCHEMBL26106019 | 0.77 | IDO1 (0.32) | AOC3MEN1KMT2AGABBR2GABBR1 | |
| SCHEMBL27999842 | 0.77 | HTT (0.37) | AOC3KDM4EMEN1KMT2ALMNA | |
| SCHEMBL22105007 | 0.77 | AOC3 (0.45) | AOC3SIGMAR1KDM4ECYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275524-A1 | NOVEL HYPOCHOLESTEROLEMIC COMPOUNDS | LIPIDEON BIOTECHNOLOGY AG | 2009-11-05 | — | — | US | disclosed |
| US-7544667-B2 | Hypocholesterolemic compounds | LIPIDEON BIOTECHNOLOGY AG (CH) | 2009-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275524-A1 | NOVEL HYPOCHOLESTEROLEMIC COMPOUNDS | CYP46A1, SREBF1, CETP | AOC3 2808/4885SIGMAR1 2481/4885KDM4E 4529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.