Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.52 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3097213 | 1.00 | LMNA (0.60) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL75953 | 1.00 | LMNA (0.60) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL8425086 | 1.00 | LMNA (0.60) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| Ammonia Solution, Strong SCHEMBL3568139 | 0.98 | LMNA (0.58) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL11251295 | 0.89 | LMNA (0.54) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| Benzoic Acid SCHEMBL569379 | 0.87 | DAO (0.50) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL13433805 | 0.86 | LMNA (0.60) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL477671 | 0.86 | LMNA (0.60) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL13433806 | 0.86 | LMNA (0.60) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL7125858 | 0.85 | KDM4E (0.46) | LMNAKDM4EL3MBTL1AOC3RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137691-A2 | 1,3-DIOL SYNTHESIS VIA CONTROLLED, RADICAL-MEDIATED C-H FUNCTIONALIZATION | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-11-12 | — | — | WO | disclosed |