Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4248134 | 0.91 | LMNA (0.64) | LMNATSHRALPGSMN1; SMN2FAAH | |
| SCHEMBL4453428 | 0.90 | TSHR (0.56) | LMNATSHRSMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL13671111 | 0.88 | LMNA (0.54) | LMNATSHRALPGSMN1; SMN2FAAH | |
| SCHEMBL13671109 | 0.88 | LMNA (0.56) | LMNATSHRPOLB | |
| SCHEMBL4450270 | 0.88 | LMNA (0.56) | LMNATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL4456715 | 0.87 | LMNA (0.53) | LMNATSHRCTDSP1 | |
| SCHEMBL4456969 | 0.83 | TSHR (0.51) | LMNATSHRALPGSMN1; SMN2FAAH | |
| SCHEMBL4453699 | 0.83 | LMNA (0.53) | LMNATSHRSMN1; SMN2FAAHTRPV1 | |
| SCHEMBL4453413 | 0.79 | LMNA (0.46) | LMNATSHRSMN1; SMN2FAAHTRPV1 | |
| SCHEMBL4450861 | 0.79 | LMNA (0.46) | LMNATSHRALPGSMN1; SMN2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009132452-A1 | DIARYL-CYCLYLALKYL DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | NEUROMED PHARMACEUTICALS LTD. (CA) | 2009-11-05 | — | — | WO | disclosed |