Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.33 |
| ▸ | ALPL | P05186 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.32 |
| ▸ | SPR | P35270 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1986508 | 0.88 | CNR1 (0.45) | CNR1CNR2CHRNA7ALDH1A1LMNA | |
| SCHEMBL1989388 | 0.84 | CNR1 (0.49) | CNR1CNR2CHRNA7ALDH1A1LMNA | |
| SCHEMBL1985064 | 0.82 | CNR1 (0.45) | CNR1CNR2CHRNA7ALDH1A1NPBWR1 | |
| SCHEMBL1985957 | 0.81 | CNR1 (0.44) | CNR1CNR2CHRNA7ALDH1A1SPR | |
| SCHEMBL1987486 | 0.80 | CNR1 (0.49) | CNR1CNR2CHRNA7ALDH1A1LMNA | |
| SCHEMBL1985657 | 0.79 | CNR1 (0.45) | CNR1CNR2CHRNA7ALDH1A1LMNA | |
| SCHEMBL1985005 | 0.79 | CNR1 (0.49) | CNR1CNR2CHRNA7ALDH1A1LMNA | |
| SCHEMBL1985692 | 0.78 | CNR1 (0.41) | CNR1CHRNA7ALDH1A1 | |
| SCHEMBL1986377 | 0.78 | CNR1 (0.40) | CNR1CNR2CHRNA7ALPLCYP46A1 | |
| SCHEMBL1986178 | 0.78 | CNR1 (0.42) | CNR1CNR2CHRNA7ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009141532-A2 | PYRROLE DERIVATIVES, PREPARATION OF SAME AND THERAPEUTIC APPLICATION THEREOF | SANOFI-AVENTIS (FR) | 2009-11-26 | — | — | WO | disclosed |