Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 2/20 | 0.66 |
| ▸ | CASP6 | P55212 | 2/20 | 0.66 |
| ▸ | RAD52 | P43351 | 2/20 | 0.57 |
| ▸ | CASP7 | P55210 | 1/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 8/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 8/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 4/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | FGB | P02675 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14514560 | 0.90 | NSD2 (0.70) | NSD2CASP6RAD52CASP7HSP90AA1 | |
| SCHEMBL13608928 | 0.88 | NSD2 (0.67) | NSD2CASP6RAD52CASP7HSP90AA1 | |
| SCHEMBL4973244 | 0.84 | NSD2 (0.62) | NSD2CASP6RAD52CASP7HSP90AA1 | |
| SCHEMBL10731810 | 0.81 | NSD2 (0.71) | NSD2CASP6RAD52CASP7HSP90AA1 | |
| SCHEMBL10731681 | 0.81 | NSD2 (0.71) | NSD2CASP6RAD52CASP7HSP90AA1 | |
| SCHEMBL8902067 | 0.81 | NSD2 (0.70) | NSD2CASP6RAD52CASP7HSP90AA1 | |
| SCHEMBL4726902 | 0.81 | NSD2 (0.70) | NSD2CASP6RAD52CASP7HSP90AA1 | |
| SCHEMBL13609321 | 0.80 | NSD2 (0.58) | NSD2CASP6RAD52CASP7HSP90AA1 | |
| Hydrochloric Acid SCHEMBL11541621 | 0.80 | NSD2 (0.69) | NSD2CASP6RAD52CASP7HSP90AA1 | |
| SCHEMBL14424700 | 0.79 | NSD2 (0.65) | NSD2CASP6RAD52CASP7HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090291923-A1 | TRIOXANE DIMERS HAVING HIGH ANTICANCER AND LONG-LASTING ANTIMALARIAL ACTIVITIES | JOHNS HOPKINS UNIVERSOTY (US) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291923-A1 | TRIOXANE DIMERS HAVING HIGH ANTICANCER AND LONG-LASTING ANTIMALARIAL ACTIVITIES | HCCS, XPO5, DHX15 | NSD2 2284/4885CASP6 149/4885RAD52 648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.