Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCNN1A | P37088 | 15/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.39 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.35 |
| ▸ | CBR1 | P16152 | 1/20 | 0.35 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL707971 | 0.89 | SCNN1A (0.55) | SCNN1A | |
| SCHEMBL12442498 | 0.84 | SCNN1A (0.41) | SCNN1A | |
| SCHEMBL12443281 | 0.81 | SCNN1A (0.47) | SCNN1A | |
| SCHEMBL12443046 | 0.81 | SCNN1A (0.55) | SCNN1A | |
| SCHEMBL12442490 | 0.81 | SCNN1A (0.55) | SCNN1A | |
| SCHEMBL12442500 | 0.80 | SCNN1A (0.41) | SCNN1A | |
| SCHEMBL15839506 | 0.80 | SCNN1A (0.39) | SCNN1A | |
| SCHEMBL10028705 | 0.80 | SCNN1A (0.65) | SCNN1A | |
| SCHEMBL13979964 | 0.80 | SCNN1A (0.40) | SCNN1A | |
| SCHEMBL14252050 | 0.79 | SCNN1A (0.50) | SCNN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009139948-A1 | POLY AROMATIC SODIUM CHANNEL BLOCKERS | JOHNSON MICHAEL R (US) | 2009-11-19 | — | — | WO | disclosed |