SCHEMBL13620749

SCHEMBL13620749

CCCCOc1ccc2cc(CCCCNC(=N)NC(=O)c3nc(Cl)c(N)nc3N)ccc2c1

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SCNN1A P37088 20/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL706204 0.97 SCNN1A (0.51) SCNN1A
SCHEMBL706632 0.95 SCNN1A (0.49) SCNN1A
SCHEMBL10110738 0.93 SCNN1A (0.51) SCNN1A
SCHEMBL710026 0.93 SCNN1A (0.52) SCNN1A
SCHEMBL10115655 0.93 SCNN1A (0.53) SCNN1A
SCHEMBL14268265 0.93 SCNN1A (0.59) SCNN1A
SCHEMBL17806175 0.90 SCNN1A (0.56) SCNN1A
SCHEMBL10028720 0.90 SCNN1A (0.58) SCNN1A
SCHEMBL10110728 0.90 SCNN1A (0.47) SCNN1A
SCHEMBL12443365 0.87 SCNN1A (0.53) SCNN1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009139948-A1 POLY AROMATIC SODIUM CHANNEL BLOCKERS JOHNSON MICHAEL R (US) 2009-11-19 WO disclosed