Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.39 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.36 |
| ▸ | MAP1LC3A | Q9H492 | 2/20 | 0.36 |
| ▸ | POLQ | O75417 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10306468 | 1.00 | HSP90AA1 (0.39) | HSP90AA1HSP90AB1MAP1LC3BMAP1LC3APOLQ | |
| SCHEMBL13609342 | 1.00 | HSP90AA1 (0.39) | HSP90AA1HSP90AB1MAP1LC3BMAP1LC3APOLQ | |
| SCHEMBL10259547 | 1.00 | HSP90AA1 (0.39) | HSP90AA1HSP90AB1MAP1LC3BMAP1LC3APOLQ | |
| SCHEMBL7885428 | 1.00 | HSP90AA1 (0.39) | HSP90AA1HSP90AB1MAP1LC3BMAP1LC3APOLQ | |
| SCHEMBL10260098 | 0.89 | HSP90AA1 (0.36) | HSP90AA1HSP90AB1MAP1LC3BMAP1LC3APOLQ | |
| SCHEMBL10306466 | 0.89 | HSP90AA1 (0.36) | HSP90AA1HSP90AB1MAP1LC3BMAP1LC3APOLQ | |
| SCHEMBL13609344 | 0.89 | HSP90AA1 (0.36) | HSP90AA1HSP90AB1MAP1LC3BMAP1LC3APOLQ | |
| SCHEMBL13620869 | 0.89 | HSP90AA1 (0.36) | HSP90AA1HSP90AB1MAP1LC3BMAP1LC3APOLQ | |
| SCHEMBL7882575 | 0.89 | HSP90AA1 (0.36) | HSP90AA1HSP90AB1MAP1LC3BMAP1LC3APOLQ | |
| SCHEMBL6931164 | 0.86 | LGALS8 (0.32) | HSP90AA1HSP90AB1LGALS8METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622451-B2 | Novobiocin analogues as neuroprotective agents and in the treatment of autoimmune disorders | UNIVERSITY OF KANSAS (US) | 2009-11-24 | — | — | US | disclosed |