⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7600258 | 1.00 | — | — | |
| SCHEMBL16707759 | 0.85 | NCF1 (0.34) | — | |
| SCHEMBL1615410 | 0.83 | — | — | |
| SCHEMBL2756894 | 0.83 | — | — | |
| SCHEMBL6891743 | 0.83 | — | — | |
| SCHEMBL13416621 | 0.81 | CHRNB4 (0.43) | — | |
| SCHEMBL7600904 | 0.81 | CHRNB4 (0.43) | — | |
| SCHEMBL17735692 | 0.81 | CHRNB4 (0.43) | — | |
| SCHEMBL19334296 | 0.81 | — | — | |
| SCHEMBL25020549 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230364070-A1 | PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER | ANTARES THERAPEUTICS, INC. | 2023-11-16 | — | — | US | disclosed |
| WO-2023150394-A1 | METHODS FOR TREATMENT OF CANCER | FRONTIER MEDICINES CORPORATION (US) | 2023-08-10 | — | — | WO | disclosed |
| US-20180186782-A1 | AMIDE COMPOUNDS FOR TREATMENT OF IMMUNE AND INFLAMMATORY DISORDERS | ACHILLION PHARMACEUTICALS, INC. (US) | 2018-07-05 | — | — | US | disclosed |
| WO-2009143507-A2 | SILENT DESENSITIZERS OF NEURONAL NACHR AND METHODS OF USE THEREOF | GEORGETOWN UNIVERSITY (US) | 2009-11-26 | — | — | WO | disclosed |