Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 11/20 | 0.48 |
| ▸ | PGR | P06401 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13458937 | 0.84 | NR3C1 (0.46) | NR3C1PGR | |
| SCHEMBL13431386 | 0.82 | NR3C1 (0.42) | NR3C1PGR | |
| SCHEMBL3230488 | 0.78 | NR3C1 (0.80) | NR3C1PGR | |
| SCHEMBL3235076 | 0.76 | NR3C1 (0.77) | NR3C1PGR | |
| SCHEMBL3231151 | 0.76 | NR3C1 (0.54) | NR3C1PGR | |
| SCHEMBL3237029 | 0.74 | NR3C1 (0.43) | NR3C1PGR | |
| SCHEMBL3227464 | 0.71 | NR3C1 (0.78) | NR3C1PGR | |
| SCHEMBL3236933 | 0.71 | NR3C1 (0.67) | NR3C1PGR | |
| SCHEMBL3228882 | 0.71 | NR3C1 (0.78) | NR3C1PGR | |
| SCHEMBL3231184 | 0.70 | NR3C1 (0.79) | NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2116538-A1 | CONDENSED TETRAHYDROQUINOLINE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | Mitsubishi Tanabe Pharma Corporation (JP) | 2009-11-11 | — | — | EP | disclosed |